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NFL Week 17 Fantasy Picks: Must-Start Players Revealed NOW!

NFL Week 17 Fantasy Picks: Must-Start Players Revealed NOW!
Editorial
  • PublishedDecember 24, 2025

UPDATE: As fantasy football enthusiasts gear up for Week 17, critical decisions must be made with championship implications. The stakes are high, and every lineup choice could mean the difference between victory and defeat. Here’s the latest on must-start players and those to avoid, ensuring you maximize your chances for success.

START: Baker Mayfield, Buccaneers vs. Dolphins
In a must-win situation for the Tampa Bay Buccaneers, Mayfield is set to unleash his full potential against the Miami Dolphins. With a complete set of pass catchers, he faces a favorable matchup against a top-10 QB defense. Expect fireworks as Mayfield aims to lead his team to an essential victory and deliver big for fantasy owners.

Other must-starts include:
Brock Purdy vs. Bears
Drake Maye vs. Jets
Jacoby Brissett vs. Bengals

Avoid: Justin Herbert, Chargers vs. Texans
Despite his name recognition, Herbert is facing a tough challenge against Houston’s relentless pass rush. The Chargers’ offensive line has struggled, and Herbert’s recent conservative play-calling has capped his fantasy ceiling. In championship week, fantasy players should seek higher upside options.

START: Omarion Hampton, Chargers vs. Texans
Emerging as the Chargers’ reliable early-down back, Hampton’s workload is peaking at the right time. The Texans’ run defense has vulnerabilities, and with a projected 18 to 22 touches, Hampton could be a solid RB2, especially in a critical week.

Other must-starts include:
James Cook vs. Eagles
Travis Etienne vs. Colts
Chase Brown vs. Cardinals

Avoid: Aaron Jones Sr., Vikings vs. Lions
With his value largely dependent on touchdowns, Jones faces a formidable Lions defense that excels at limiting rushing scores. In a week where every point counts, he presents more risk than reward.

START: Jaylen Waddle, Dolphins vs. Buccaneers
Waddle is poised to be a game-changer in this high-octane matchup. Tampa Bay’s secondary struggles against speed receivers, and Waddle, as Miami’s top target, could explode for significant fantasy points. Expect aggressive passing as the Dolphins look to exploit this matchup.

Other must-starts include:
Tee Higgins vs. Cardinals
Jauan Jennings vs. Bears
CeeDee Lamb vs. Commanders

Avoid: Terry McLaurin, Commanders vs. Cowboys
The Commanders’ starting quarterback situation is shaky, with third-string QB Josh Johnson at the helm. This instability greatly diminishes McLaurin’s fantasy potential against a tough Cowboys defense.

START: Hunter Henry, Patriots vs. Jets
Henry is becoming a key target for New England, particularly in critical situations. The Jets’ defense allows tight ends to thrive in the middle of the field, and Henry’s consistent targets make him a dependable TE1.

Other must-starts include:
Trey McBride vs. Bengals
Juwan Johnson vs. Titans
Theo Johnson vs. Raiders

Avoid: Mark Andrews, Ravens vs. Packers
Struggling to regain his past form, Andrews has not surpassed 50 yards all season, making him a risky choice in a week where upside is essential.

With championship week upon us, these critical updates are vital for fantasy football players. Make your roster decisions wisely, and stay tuned for more updates as the week progresses!

Editorial
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Editorial

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