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Pfizer COVID-19 Vaccine Sales Plunge 25% Amid New Guidelines

Pfizer COVID-19 Vaccine Sales Plunge 25% Amid New Guidelines
Editorial
  • PublishedNovember 4, 2025

BREAKING: Pfizer’s U.S. sales of its COVID-19 vaccine, Comirnaty, have plunged 25% as new government guidelines narrow recommendations on who should receive the shots. The latest sales report reveals a significant drop from $1.16 billion last year to $870 million in the third quarter of 2023, indicating a troubling trend for the pharmaceutical giant.

The Centers for Disease Control and Prevention (CDC) recently shifted its stance, stating that COVID-19 vaccinations are no longer universally recommended. This decision, made public in September, has left many potential vaccine recipients confused about their eligibility and necessity. The CDC’s new guidelines allow individuals to make their own choices, a departure from previous recommendations for annual boosters for all Americans aged six months and older.

The timing of the updated guidance coincides with the typical fall vaccination season, which is crucial for Americans seeking protection against potential winter surges of the virus. However, experts warn that public interest in COVID-19 shots is waning, fueled by rising anti-vaccine sentiments and uncertainty regarding their effectiveness.

Dr. Amesh Adalja from the Johns Hopkins Center for Health Security pointed out that vaccination rates have been “suboptimal,” particularly among high-risk groups. “That’s only going to fall off more this season,” he stated, highlighting the urgency of addressing public confusion.

The recent changes have also raised questions about insurance coverage for the shots. America’s Health Insurance Plans confirmed that its members will continue to cover COVID-19 vaccinations, but the lack of clarity has prompted concern among patients. CVS Health has taken steps to alleviate some of this confusion by announcing that prescriptions will not be required for vaccinations at their stores and clinics.

Theresa Tolle, owner of Bay Street Pharmacy in Sebastian, Florida, noted that this fall has been particularly perplexing for her customers. While many older patients still seek the vaccine, she has encountered more individuals expressing hesitance. “There’s just so many messages out there, they don’t know who to believe,” Tolle remarked. “I’ve had people tell me they are afraid of it when they’ve had it many times.”

Pfizer’s declining sales signal a broader trend in the market, with analysts predicting that rival Moderna‘s vaccine, Spikevax, will see a sales drop of approximately 50% in the same quarter. Moderna is set to release its third-quarter results on Thursday, and the industry is watching closely to assess the ongoing impact of the shifting vaccination landscape.

As the fall vaccination season progresses, the urgency for clear communication and reliable information becomes paramount. Public health officials and pharmacies alike are tasked with navigating this critical moment, ensuring that the public remains informed and protected as we head into winter.

Stay tuned for further updates as this developing situation unfolds.

Editorial
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Editorial

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